Cryopreservation is an essential tool for efficient mouse colony management and safeguarding your valuable models from strain loss. At JAX, we offer both sperm and embryo cryopreservation, with flexible short- and long-term storage options to meet your needs. With over 22,000 strains successfully cryopreserved and recovered, our industry-leading protocols and advanced cryoprotectant solutions ensure the long-term viability of your samples.
You’ve dedicated immense time and resources to your models—don’t leave them vulnerable. Protect your research from delays caused by strain loss due to breeding cessation, genetic drift, natural disasters, or other unforeseen events.
Why Choose JAX for Cryopreservation?
Pioneers & Industry Standard: We developed the technology and continue to set the benchmark.
Double Security: All samples are stored in two geographically separated facilities, protecting your investment from freezer failure or natural disasters.
Rapid & Scalable Recovery: Recover with speed expansion via IVF to quickly generate large cohorts when you need them.
Cost Efficiency: Reduce colony maintenance expenses by freezing low-use strains.
Cost-benefit of cryopreserving versus maintaining live colonies of low use research strains
The cost to maintain a heterozygous colony that requires frequent genotyping ranges from a few thousand to 10's of thousands per year. Even in a scenario with low per diem rates, the cumulative cost of maintaining a colony increases significantly faster than the cumulative cost of cryopreserving a strain, even if a couple recoveries need to be done.
The decision to cryopreserve your strain is the first step in protecting it from unforeseen circumstances. How you choose to cryopreserve depends on the unique characteristics of your strain. JAX has successfully refined the embryo cryopreservation technique for more than 30 years to recover mice quickly and reliably. The JAX Sperm Cryopreservation method was developed by our reproductive science experts and has become the industry standard.
What you will get:
Speak to JAX about your Sperm Cryo Project
Standard Approach:
Custom Approach:
What you will get:
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Advantages |
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Timeline | Cryopreservation is typically completed within four to six weeks | |
Limitations | Requires several mice from your colony (2+ males (8-16 wks old) and at least 8-12 females (4-12 wks old)) |
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Future Use | Embryo cryo is better for more frequently used strains or when rapid recovery is necessary | Sperm cryo often a better option for low-use strains |
Budget | Up-front costs associated with Embryo Cryo are higher, yet less time and resources are required for recovery | Up-front costs associated with Sperm cryo are lower, but may take more resources to obtain the desired genotype |
Need to cryopreserve your strain in an emergency or in the convenience of your own lab? JAX's Sperm Cryopreservation Kit allows researchers to:
Each Sperm Cryo Kit Includes:
After you have preserved your models, ship your samples to JAX for storage in our secure facilities. When you are ready to recover your strain, use our cryorecovery service to regenerate your colony.
Pricing:
5 Strain Kit: $2,165.00
JAX maintains over 14,000 strains in a cryopreserved state. All storage tanks are auto filled, alarmed, routinely inspected and under 24/7 surveillance in secure facilities. We divide samples among multiple tanks in multiple locations for additional safety and security.
Benefits & Capabilities
The Jackson Laboratory efficiently maintains a repository of over 14,000 mouse strains while upholding the principles of the 3Rs. In this presentation, we share a data-supported framework, derived from years of experience, to optimize decisions regarding animal research colonies. This framework is designed to trim costs, save time, and reduce the number of animals used for colony maintenance and cohort production.
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